Infometrix LineUp: The Solution
LineUp is an easy to use and statistically valid
software application. LineUp establishes a
target “gold standard” calibration file.
Subsequent runs are “aligned” to conform to
the gold standard retention time within user
set statistical limits and without effect on peak
values. Fully integrated and automated,
LineUp is a application module called by
standard EZChrom GC control and data
handling software from Agilent. LineUp
produces a data file that can either be
manually or automatically processed by
standard EZChrom, or delivered to Infometrix
Pirouette software for chemometric
applications, including Principal Component
Analysis, Multiple Linear Regression,
Partial Least Squares and other valuable
interpretive applications.
Instrumental Variance:
The Measurement Problem
All XY data varies at some level or another,
whether in spectroscopy where both
wavelength and absorbance can vary, or gas
chromatography where retention time and
peak areas can vary. Regardless of how well
controlled the analytical system is, even
simple measurements need correct data
interpretation, including accurate peak
identification by retention time and validation
of the measurement system performance.
Fast gas chromatography makes GC work
more like spectroscopy. With 10’s or 100’s of
chromatographic results produced per hour,
automating the data interpretation process
becomes highly desirable, if not an
absolute requirement.
Use of Chemometrics in
Fast GC Analysis